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We found that p21WAF-1 expression is up-regulated by CC-4047 and lenalidomide and is, at least in part, responsible for cell cycle arrest in G1 phase in Namalwa cells.
On 7 September 2009, a ‘Compliance Communication' letter was issued to healthcare professionals who purchase Revlimid® by the Compliance Department of HSA to tell them of the protection monitoring protocols which have been imposed on the prescribing and doling out of lenalidomide (Revlimid®), a doubtlessly teratogenic drug marketed by Celgene Pte Ltd.
revlimid from canada is a known human teratogen that causes life-threatening human beginning defects or embryo-fetal dying see Use in Particular Populations (eight.1) An embryo-fetal growth research in monkeys indicates that lenalidomide produced malformations in the offspring of female monkeys who received the drug throughout being pregnant, similar to start defects observed in humans following publicity to thalidomide during pregnancy.
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