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POMALYST Dexamethasone Trial Design

Среда, 08 Января 2020 г. 15:38 + в цитатник

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This claims database examine showed that sufferers receiving lenalidomide-solely repairs treatment remained on remedy for >1 yr (median 15.5 months) had an extended time to subsequent remedy, and had been less most likely than sufferers receiving no upkeep remedy to experience sickness development inside the research time interval.
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We gratefully acknowledge the numerous colleagues in the Amyloid Therapy and Research Program, Medical Trials Workplace, and Center for Most cancers and Blood Issues at Boston University Medical Middle who assisted with the multidisciplinary evaluation and treatment of the patients with AL amyloidosis.
Females of reproductive potential must use 2 forms of contraception or continuously abstain from heterosexual intercourse throughout and for 4 weeks after REVLIMID treatment see Warnings and Precautions (5.1) , and Treatment Information (17) To keep away from embryo-fetal exposure to lenalidomide, REVLIMID is only out there through a restricted distribution program, the REVLIMID REMS® program (5.2).
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Revlimid, considered one of Celgene's merchandise, is used to treat various cancers, similar to multiple myeloma, but additionally poses significant dangers to fetal growth, inflicting life-threatening deformities and abnormalities when uncovered to sufferers during being pregnant.
Trial information showed the triple Imnovid mixture remedy significantly increased the time sufferers lived with out disease development in contrast with these in the management group (11.2 months vs. 7.1 months), successfully reducing the chance of disease progression by 39%.
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